ZLab研究成果汇总

蛋白质设计

Simplifying in silico protein evolution with minimal screening by unZipro

Zhaohui Qin^†, Sanzeng Zhao^†, Zhaolong Deng^†, Xiaomin Si^†, Cheng Xing, Zhenfei Zhang, Yumeng Zhang, Xueying Han, Jindong Zhang, Yang Chen, Xiaoyi Liu, Jinhui Li, Lei Fu, Liyuan You, James W. Murray, Huiyun Liu, Huifang Li, Chengwei Li, Song Wu, Junzhou Li, Zhen Chen^*, Jiangning Song^*, Daowen Wang^*, Xiang Ji^*

Molecular Cell

蛋白质功能预测

PlantPTM: A deep learning framework integrating protein language models with multi-view features for predicting diverse post-translational modification sites in plants

Gensheng Dou^†*, Kaiyuan Wang^†, Zhaohui Qin^†, Min Zhang, Wentian Zhang, Chunbo Miao, Junzhou Li^*, Zhen Chen^*.

Molecular Plant

基因组编辑

Efficient homologous replacement and deletion of large genomic fragments through template-jumping prime editing in rice

Huixia Liu^†, Y. Wang^†, S. Guan^†, Z. Zhang, Zhaohui Qin, D. Zhao, F. Li, Min Zhang, Wentian Zhang, Y. Du, Junzhou Li, Zhen Chen^*, Chunbo Miao^*.

New Phytologist

AI sheds new light on genome editing

Zhaohui Qin (秦兆辉)^†, Zhaolong Deng (邓兆龙)^†, Chengwei Li (李成伟), Daowen Wang (王道文), Xiang Ji (姬祥)^*, Zhen Chen (陈震)^*.

Trends in Biotechnology

SLAM: Structure-aware lysine β-hydroxybutyrylation prediction with protein language model

Zhaohui Qin^†, Huixia Liu^†, Pei Zhao, Kaiyuan Wang, Haoran Ren, Chunbo Miao, Junzhou Li^*, Yong-Zi Chen^*, Zhen Chen^*.

International Journal of Biological Macromolecules

Current computational tools for protein lysine acylation site prediction

Zhaohui Qin^†, Haoran Ren^†, Pei Zhao^†, Kaiyuan Wang, Huixia Liu, Chunbo Miao, Yanxiu Du, Junzhou Li^*, Liuji Wu^*, Zhen Chen^*

Briefings in Bioinformatics

iFeatureOmega: an integrative platform for engineering, visualization and analysis of features from molecular sequences, structural and ligand data sets

Zhen Chen^†, Xuhan Liu^†, Pei Zhao^†, Chen Li^†, Yanan Wang, Fuyi Li, Tatsuya Akutsu, Chris Bain, Robin B Gasser, Junzhou Li, Zuoren Yang^*, Xin Gao^*, Lukasz Kurgan^*, Jiangning Song^*.

Nucleic Acids Research

iLearnPlus: a comprehensive and automated machine-learning platform for nucleic acid and protein sequence analysis, prediction and visualization

Zhen Chen^†, Pei Zhao^†, Chen Li^†, Fuyi Li, Dongxu Xiang, Yong-Zi Chen, Tatsuya Akutsu, Roger J Daly, Geoffrey I Webb, Quanzhi Zhao^*, Lukasz Kurgan^*, Jiangning Song^*.

Nucleic Acids Research